New York police officers attempted to keep the groups separated, but videos posted to social media showed protestors breaking free in an attempt to physically assault one another.
Both the pro-Israel and pro-Palestine groups were relatively small, but their shouts and repeated attempts to attack one another drew a crowd in front of the Israeli consulate in Manhattan.
A much larger group of pro-Palestinian supporters marched through New York City, carrying banners condemning Israeli actions.
New York Mayor Bill de Blasio could not be immediately reached by Fox News for comment.
Due to safety precautions, staff members at the Israeli consulate in New York City were sent home ahead of Tuesday’s protest, the Times of Israel first reported.
Rallies in support of Palestine have popped up globally, with several events scheduled in the U.S., Canada, the United Kingdom and Europe.
Another “All Out For Palestine” protest is expected in New York Wednesday.
Since Monday, Israel and Palestine have exchanged rocket fire, resulting in hundreds of injuries and the deaths of at least two Israelis and 32 Palestinians.
Special Coordinator for the Middle East Peace Process Tor Wennesland urged Israelis and Palestinians to stop their aggressive retaliatory actions Tuesday night, warning against “a full-scale war.”
“Leaders on all sides have to take the responsibility of de-escalation,” he said in a statement. “The cost of war in Gaza is devastating & is being paid by ordinary people. UN is working with all sides to restore calm. Stop the violence now.”